A popular erectile dysfunction drug - Tadalafil - may also improve lower urinary tract symptoms in men with an enlarged prostate (benign prostatic hyperplasia). The researchers behind the discovery presented their findings at the 104th Annual Scientific Meeting of the American Urological Association (AUA). In their study, the researchers randomly separated 200 men, with an age equal to or older than 40 years, into two groups taking either 20 mg of tadalafil once daily or a placebo. After 12 weeks of treatment, the men taking tadalafil experienced improved urinary flow rate, peak flow rate, bladder capacity and bladder voiding efficiency. At the end of the study, the proportion of obstructed patients in the placebo group increased, while the proportion in the tadalafil group decreased.
"[This adds] further evidence to the growing body of research that suggests that in addition to their well known effect on erectile dysfunction, PDE-5 inhibitors [such as tadalafil] may be able to help with management of bladder outlet symptoms as well. This is an exciting concept for men's health," said Anthony Y. Smith, an AUA spokesperson.
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Source: American Urological Association