Home Page
The latest articles, features and news.



Read About...

Adolescence
AIDS/HIV Treatments
Andropause
Assisted Reproduction
Circumcision
Dating
Dicks & History
Enlargement
Fertility
Firefly Talks Dicks
Gay and Bi
Gender
Getting It Up
Male Peculiarities
Paternity
Pecker Problems
Penis Size
Prostate Cancer
Relationships
STDs


Search Articles

Custom Search



Discussion Forums


Q and A
Sexuality
Dating
Size
Pics





22 August 2008
PSA test skewed by obesity
by George Atkinson

The test for elevated levels of prostate-specific antigen (PSA) to detect prostate cancer appears to be biased against obese men, whose PSA levels tend to be deceptively low, say researchers from the Duke University Prostate Center. This bias, they explain, may be creating more aggressive cancers by delaying diagnosis.

"We know that obese men tend to have lower PSA values than their normal-weight counterparts, possibly caused by larger blood volumes which dilute the readings," said Duke urologist Stephen Freedland, who led the research. "Now we know some of the real implications of this - that these men are at a disadvantage in terms of prognosis compared to normal-weight men."

Freedland's team used patient data to examine the association between body mass index (BMI) and the amount of disease discovered after surgery to remove the prostate. "We compared men who had their cancers detected by PSA screening to those who had an abnormal digital rectal exam, which may not confer the same bias against obese men," Freedland said.

The researchers looked at a total of nearly 3,400 men and found that obese men whose cancer was diagnosed by PSA testing had more than twice the risk of cancer recurrence after surgery than their normal-weight counterparts. "In contrast, obese men with abnormal digital rectal exams had similar outcomes as normal-weight men," Freedland explained.

The researchers are hopeful that this data, coupled with the earlier data on which it builds, may be a catalyst to encourage alternative screening methods for obese men, or a lower threshold for worrisome PSA levels in obese men. "Obesity is very common in the United States, so this potentially affects a lot of people," Freedland said. "We can't forget that when we use the term obese we are not just talking about very, very large men. A man who is 5 foot 9 and weighs 203 pounds would be considered obese."

Related:
Weight A Big Factor In Prostate Cancer Survival
Weight Gain Can Turbocharge Prostate Cancer
Prostate Cancer Slowed With Low Fat Diet
Obesity Hinders Detection Of Prostate Cancer

Source: Duke University Medical Center




Home Page    Contact Us    Privacy


Your use of this website indicates your agreement to our terms and conditions of use.
Copyright 2000 - 2012 altPenis.com and its licensors. All rights reserved.